Cellular rejuvenation
For men reclaiming their hairline and women reclaiming their complexion — five precision-formulated products targeting every root cause of hair loss, skin aging, and grey reversal.
The system
Each product targets a distinct biological mechanism. Nothing overlaps. Nothing is redundant.
Two audiences. One formula.
GHK-Cu is one of the most studied actives in both hair restoration and anti-aging skincare. Same formula — two completely different transformations.
For men
Rebuilding the hairline
GHK-Cu at 2% signals dormant follicles to reactivate, blocks DHT through four independent pathways, and suppresses PGD2 — the hidden second driver of hair loss that most brands have never heard of. Nine mechanisms targeting frontal thinning simultaneously.
For women
Reversing skin aging
The same 2% GHK-Cu stimulates collagen and elastin production, reduces the depth of fine lines, improves skin firmness, and accelerates cellular renewal. Apply to face and neck like a premium anti-aging serum. Centella Asiatica adds brightening and healing.
Why it works
Every ingredient has published evidence. Every mechanism is distinct. Nothing in this system is decoration.
Phospholipid encapsulation delivers actives 7x deeper than standard serums — reaching the follicle bulb and dermis where the science actually happens.
Prostaglandin D2 is a hidden second driver of hair loss most brands don't target. Essoir I suppresses it with quercetin and ecklonia cava — ingredients with human cell evidence.
NAD+ and methylene blue restore cellular energy from two independent angles — precursor replenishment and direct electron transport enhancement.
Methylene blue photosensitizes the scalp for 650–850nm red light — amplifying photobiomodulation significantly beyond what either achieves alone.
Grass-fed tallow's sebum-mimicking fatty acid profile is one of nature's most effective carriers for actives deep into the hair follicle canal.
Catalase directly breaks down hydrogen peroxide — the root cause of hair bleaching from within. L-tyrosine then fuels new melanin production.
The routine
Every product has a clear role. Each step prepares or amplifies the next.
Bundles
Every product is stronger with the others. Save when you commit to the full system.
All products
Five products. Five steps. Complete cellular rejuvenation — for men targeting hair loss and women targeting skin aging.
The science
Every ingredient in every product has published evidence. Here is the full science behind each mechanism.
Phosphatidylcholine liposomes encapsulate actives in phospholipid bilayers that bypass the stratum corneum — delivering GHK-Cu, NAD+, and methylene blue directly to the dermis and follicle bulb rather than sitting on the surface.
University of Pennsylvania researchers found PGD2 is significantly elevated in bald scalp and directly inhibits hair growth. Quercetin inhibits PTGDS enzyme. Ecklonia cava polyphenols have outperformed minoxidil in human dermal papilla cell proliferation studies.
Essoir I targets 5-alpha reductase from four angles simultaneously: saw palmetto, rosemary extract (comparable to minoxidil in RCT at 6 months), pumpkin seed oil (44% reduction in hair fall, human RCT), and zinc PCA.
NAD+ declines with age, reducing mitochondrial function in follicle cells. Topical liposomal NAD+ with NMN precursor delivers directly to the scalp — bypassing the systemic absorption inefficiency of oral supplementation.
Applied before 650–850nm red light therapy, methylene blue acts as a photosensitizer creating a photodynamic amplification effect. Significantly enhances the photobiomodulation stimulus to follicle cells beyond what RLT alone achieves.
Hair greys through hydrogen peroxide accumulation bleaching the shaft from within. Catalase directly neutralizes H2O2. L-tyrosine provides the raw melanin precursor. Fo-Ti supports melanocyte function through traditional pathways.
Grass-fed tallow's oleic, palmitic, and stearic acids mirror human sebum ratios closely. The whipping process creates a lightweight aerated texture that absorbs without greasiness while maintaining exceptional follicle canal penetration.
Essoir Zero combines sulfur (antifungal + keratolytic), zinc oxide (antimicrobial + barrier repair), salicylic acid (follicle clearing), and mixed tocopherols (anti-inflammatory) to prep the scalp for maximum treatment absorption.
Key ingredients
| Ingredient | Product | Concentration | Evidence |
|---|---|---|---|
| GHK-Cu (Copper Tripeptide-1) | Essoir I | 2% | Multiple human clinical trials — hair and skin |
| Ecklonia Cava Extract | Essoir I | 1% | Beats minoxidil in human DPC proliferation studies |
| Pumpkin Seed Oil | Essoir I | 1% | Human RCT — 44% reduction in hair fall over 8 weeks |
| Rosemary Extract | Essoir I | 2% | Human RCT — comparable to minoxidil at 6 months |
| NAD+ (liposomal) | Essoir II | 1% | Foundational cellular biology + human longevity trials |
| NMN | Essoir II | 0.5% | Human clinical trials — NAD+ precursor efficacy |
| Methylene Blue (USP) | Essoir III | 0.05% | Decades of clinical use — emerging cosmetic RLT research |
| Catalase | Essoir IV | 0.5% | Mechanistic — H2O2 degradation well established |
| Sulfur + Zinc Oxide + Salicylic Acid | Essoir Zero | 3%/2%/1% | Long dermatological clinical history |
Daily routine
Every product has a clear role. The sequence matters — each step prepares or amplifies the next.
FAQ
Shop
Save when you commit to the full Essoir system. Every product is stronger with the others.
Subscribe and save
Lock in your routine and save 15% every order. Cancel anytime.
| Product | Retail | Monthly sub | Annual saving |
|---|---|---|---|
| Essoir Zero | $14.99 | $12.74 | $26.97 |
| Essoir I | $69.99 | $59.49 | $125.98 |
| Essoir II | $54.99 | $46.74 | $98.98 |
| Essoir III | $39.99 | $33.99 | $71.98 |
| Essoir IV | $49.99 | $42.49 | $89.98 |
| Full system | $229.95 | $195.46 | $413.88/year |
Our story
Essoir wasn't created in a lab by scientists who never experienced hair loss. It was built by someone who noticed their own frontal hairline thinning, obsessed over the science, tested every product on the market, and kept asking why nobody had combined these mechanisms into one clean system.
The name comes from two French words — essor, meaning growth and upward momentum, and soin, meaning care and repair. That tension between pushing forward and healing what's been lost is at the heart of everything we make.
No pharmaceuticals. No compromise. Built for men reclaiming their hairline and women reclaiming their complexion — the same science, two completely different transformations.
ESSOIR
Cellular rejuvenation
Our values
Every ingredient has published evidence. We don't formulate with hope — we formulate with data.
No minoxidil. No finasteride. Nine natural biological pathways instead of one pharmaceutical shortcut.
Grass-fed tallow, vanilla, centuries-old botanicals — traditional knowledge combined with cellular science.
Premium ingredients at accessible prices. Science shouldn't require a luxury budget or a prescription.